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10 Best Calming Products For Cats 2025 in the United States
#1
Winner
Vetoquinol Zylkene Calming Support Supplement for Small Dogs and Cats, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs and Cats, 75mg
The Vetoquinol Zylkene Calming Supplement is designed to help small dogs and cats manage stress from situations like travel, vet visits, or loud noises. Its main calming ingredient, alpha-casozepine, comes from a milk protein, making it a natural option that avoids drowsiness or harsh side effects commonly seen in other calming products.
Rating
10.0
Chosen by1,111
Type of Calming Product
Ingredients
Ease of Use
Most important from
3557 reviews
#2
FELIWAY® Optimum 30 Day Cat Calming Refill for Pheromone Diffuser, 48ml - Helps Reduce Common Signs of Stress in Cats & Kittens, Enhanced Calming
The FELIWAY Optimum Enhanced Calming Pheromone is a 30-day refill designed to reduce stress-related behaviors in cats, such as scratching, urine spraying, and excessive hiding. As a non-sedating and drug-free solution, it releases pheromone analogs to provide a natural, reassuring message to cats, helping them feel more at ease. This product is easy to use—simply plug the diffuser into an open outlet with good air circulation, and it will work continuously for up to 30 days.
Rating
8.5
Duration of Effect
Ease of Use
Cat's Preferences
Most important from
12653 reviews
#3
Calming Chews for Cats - Cat Anxiety Relief + Helps Reduce Stress - Behavioral Support & Promotes Relaxation for Travel, Boarding, Vet Visits, Separation Anxiety - Chicken (30-Day Supply)
Pet Honesty Calming Chews for Cats are designed as tasty, easy-to-give treats that help reduce anxiety and promote relaxation in cats, especially during stressful events like travel, vet visits, or separation. They feature natural calming ingredients such as L-Theanine, L-Tryptophan, Chamomile, and Thiamine (Vitamin B1), which support the nervous system and help soothe anxious behavior. The chews come in a crunchy and creamy chicken flavor that many cats find appealing, making administration less challenging.
Rating
7.9
Duration of Effect
Cat's Preferences
Ingredients
Most important from
23166 reviews
Top 10 Best Calming Products For Cats 2025 in the United States
#1
Winner
Vetoquinol Zylkene Calming Support Supplement for Small Dogs and Cats, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs and Cats, 75mg
Vetoquinol Zylkene Calming Support Supplement for Small Dogs and Cats, Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs and Cats, 75mg
Type of Calming Product: Calming Supplement
Ingredients: alpha-casozepine from milk protein
Ease of Use: Capsules to sprinkle over food
Cat's Preferences: Lactose-free, gentle on stomach
Safety and Side Effects: No drowsiness or harsh side effects
Chosen by 1111 this week
FELIWAY® Optimum 30 Day Cat Calming Refill for Pheromone Diffuser, 48ml - Helps Reduce Common Signs of Stress in Cats & Kittens, Enhanced Calming
FELIWAY® Optimum 30 Day Cat Calming Refill for Pheromone Diffuser, 48ml - Helps Reduce Common Signs of Stress in Cats & Kittens, Enhanced Calming
Type of Calming Product: Enhanced Calming Pheromone
Ingredients: Pheromone analogs
Duration of Effect: 30 days
Ease of Use: Plug into an open outlet
Safety and Side Effects: Safe for cats, humans, pets
Calming Chews for Cats - Cat Anxiety Relief + Helps Reduce Stress - Behavioral Support & Promotes Relaxation for Travel, Boarding, Vet Visits, Separation Anxiety - Chicken (30-Day Supply)
Calming Chews for Cats - Cat Anxiety Relief + Helps Reduce Stress - Behavioral Support & Promotes Relaxation for Travel, Boarding, Vet Visits, Separation Anxiety - Chicken (30-Day Supply)
Type of Calming Product: Chews
Ingredients: L-Theanine, L-Tryptophan, Chamomile, Thiamine
Duration of Effect: Varies between cats
Ease of Use: Tasty, easy-to-give treats
Cat's Preferences: Chicken flavor, crunchy, creamy texture
Safety and Side Effects: No corn, wheat, soy; no additives
TherapetMD - Cat Calming Diffuser Pheromone Kit - Multi Cat Anxiety Relief Stress Reduction Plugin 700 sq ft Coverage Vet Recommended.
TherapetMD - Cat Calming Diffuser Pheromone Kit - Multi Cat Anxiety Relief Stress Reduction Plugin 700 sq ft Coverage Vet Recommended.
Type of Calming Product: plug-in pheromone diffuser
Ingredients: natural vet-recommended dual-pheromone formula
Duration of Effect: about 30 days per refill
Ease of Use: plug in, works continuously, refill monthly
Cat's Preferences: varies by individual cat
Safety and Side Effects: fragrance-free, safe for cats and pets
FELIWAY® MultiCat 30 Day Cat Calming Refill for Pheromone Diffuser, 48ml - 1x 30 Day - Helps Reduce Conflicts and Signs of Tension in Multi-Cat Households
FELIWAY® MultiCat 30 Day Cat Calming Refill for Pheromone Diffuser, 48ml - 1x 30 Day - Helps Reduce Conflicts and Signs of Tension in Multi-Cat Households
Type of Calming Product: Pheromone
Ingredients: Pheromone
Duration of Effect: 30 days
Ease of Use: Plug into an open outlet
Safety and Side Effects: Drug-free; safe for cats and humans
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FELIWAY® Optimum 30 Day Cat Calming Plug In Pheromone Diffuser Starter Kit, 48ml - Helps Reduce Common Signs of Stress in Cats & Kittens, Enhanced Calming
FELIWAY® Optimum 30 Day Cat Calming Plug In Pheromone Diffuser Starter Kit, 48ml - Helps Reduce Common Signs of Stress in Cats & Kittens, Enhanced Calming
Type of Calming Product: Diffuser with synthetic pheromones
Ingredients: Synthetic pheromones
Duration of Effect: Up to 30 days
Ease of Use: Plug in, replace monthly
Cat's Preferences: Varies by individual sensitivity
Safety and Side Effects: Drug-free, safe, no effect on others
TopSum Cat Pheromones Calming Diffuser: Premium Pheromone Diffuser for Cats - Cat Pheromones Diffuser - Cat Calming Diffuser - Cat Calming Pheromone Diffuser (3 diffusers+ 3 Refills)
TopSum Cat Pheromones Calming Diffuser: Premium Pheromone Diffuser for Cats - Cat Pheromones Diffuser - Cat Calming Diffuser - Cat Calming Pheromone Diffuser (3 diffusers+ 3 Refills)
Type of Calming Product: plug-in diffuser with synthetic pheromones
Ingredients: synthetic cat pheromones
Duration of Effect: about 30 days per refill
Ease of Use: plug in, works quietly
Cat's Preferences: suits all ages; may not work
Safety and Side Effects: safe for regular use
FELIWAY® Classic Cat Calming Spray, 60ml - Comforts Cats at Home and On the Go and Helps to Calm During Travel
FELIWAY® Classic Cat Calming Spray, 60ml - Comforts Cats at Home and On the Go and Helps to Calm During Travel
Type of Calming Product: Spray
Ingredients: Natural feline pheromones
Ease of Use: Spray area 15 minutes before use
Cat's Preferences: 9/10 cats reduce urine spraying
Safety and Side Effects: No side effects, drug-free
COMFORT ZONE Value Kit; 3 Multicat Diffusers & 6 Refills; Cat Calming Pheromone; Reduce Stress, Aggression, Fighting, Urine Marking, Scratching
COMFORT ZONE Value Kit; 3 Multicat Diffusers & 6 Refills; Cat Calming Pheromone; Reduce Stress, Aggression, Fighting, Urine Marking, Scratching
Type of Calming Product: Plug-in diffusers with cat pheromones
Ingredients: Cat calming pheromone
Duration of Effect: Each refill lasts about one month
Ease of Use: Plug in near cats; avoid vents
Cat's Preferences: Effectiveness varies by individual cat
Safety and Side Effects: Drug-free, fragrance-free, auto shut-off
#10
COMFORT ZONE 6 Pack MultiCat Diffuser Refills; Cat Calming Pheromones Help Anxiety; 30-day refills
COMFORT ZONE 6 Pack MultiCat Diffuser Refills; Cat Calming Pheromones Help Anxiety; 30-day refills
Type of Calming Product: Calming Diffuser Refills
Ingredients: Calming pheromones
Duration of Effect: 30 days per refill
Ease of Use: Easy to use
Safety and Side Effects: Meets Intertek safety, UL certified
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Buying Guide for the Best Calming Products For Cats
Choosing the right calming product for your cat can make a significant difference in their overall well-being and behavior. Calming products can help reduce anxiety, stress, and unwanted behaviors in cats. When selecting a calming product, it's important to consider your cat's specific needs, preferences, and any underlying health conditions. Here are some key specifications to consider when choosing a calming product for your feline friend.Type of Calming ProductCalming products for cats come in various forms, including sprays, diffusers, treats, collars, and supplements. The type of product you choose depends on your cat's preferences and the specific situation. For example, diffusers and sprays are great for creating a calming environment in your home, while treats and supplements can be useful for on-the-go calming. Collars provide continuous calming effects and are ideal for cats who are comfortable wearing them. Consider your cat's comfort and the context in which the product will be used to determine the best type for your needs.
IngredientsThe ingredients in calming products can vary widely, and it's important to choose products with safe and effective components. Common ingredients include pheromones, herbal extracts like chamomile and valerian root, and amino acids such as L-theanine. Pheromones mimic the natural calming signals cats produce, while herbal extracts and amino acids can help reduce anxiety. Always check the ingredient list for any potential allergens or substances that your cat may be sensitive to. If your cat has any health conditions or is on medication, consult your veterinarian before introducing new ingredients.
Duration of EffectDifferent calming products have varying durations of effect. For instance, sprays and diffusers may provide continuous calming effects for several hours to weeks, while treats and supplements may offer temporary relief for a few hours. Collars can last for up to a month. Consider how long you need the calming effect to last when choosing a product. For ongoing anxiety, a long-lasting solution like a diffuser or collar may be more appropriate, while short-term stressors like vet visits may be better managed with treats or sprays.
Ease of UseThe ease of use of a calming product can greatly influence your decision. Some products, like diffusers and collars, require minimal effort once set up, while others, like sprays and treats, may need to be administered more frequently. Consider your lifestyle and how much time you can dedicate to using the product. If you prefer a hands-off approach, a diffuser or collar might be the best choice. If you don't mind administering a product regularly, treats or sprays could be suitable.
Cat's PreferencesEvery cat is unique, and their preferences can play a significant role in the effectiveness of a calming product. Some cats may respond better to pheromone-based products, while others may prefer the taste of calming treats. Observe your cat's behavior and reactions to different types of products to determine what works best for them. It may take some trial and error to find the most effective solution, so be patient and attentive to your cat's needs.
Safety and Side EffectsSafety is paramount when choosing a calming product for your cat. Ensure that the product is specifically designed for cats and has been tested for safety. Be aware of any potential side effects, such as drowsiness or gastrointestinal upset, and monitor your cat closely when introducing a new product. If you notice any adverse reactions, discontinue use and consult your veterinarian. Always follow the manufacturer's instructions for use and dosage to ensure your cat's safety.